CARIPAZIM

Trade name:  Caripazim

Dosage form:

Lyophilized powder for solution for external use

Composition of 1 vial:

 Enzymes, obtained from the milk-juice of the immature fruits of the melon tree (papaya). Family Caricaceae, with proteolytic activity 350 pe.The active components of the drug are: papain, chymopapain A, chymopapain B, peptidases A and B, as well as the mucolytic enzyme lysozyme.

Description:

White-yellowish lyophilized powder or porous mass with a faint specific odor.

Pharmacotherapeutic group:

Proteolytic agent of plant origin

ATC code: [D03B]

Pharmacological features:

External proteolytic agent. It removes necrotic tissues and  viscous secretion, dilutes exudates and  blood clots. Similar in action to chymotripsin and trypsin.

Therapeutic indications:

In surgical, traumatological and orthopedic, neurosurgical and neurological practice; with osteochondrosis of the spine, including with various forms of hernias of intervertebral discs and discogenic radiculitis, Schmorl's hernias, post-traumatic flexion contractures of the fingers, with keloid scars of various origins, arthrosis-arthritis of large joints, humeral-scapular periarthritis, including cerebral (cerebral) spinal arachnoiditis, neuritis of the facial nerve, tunnel syndromes.

Dosage and Directions for use:

Applied externally for the above pathology of the musculoskeletal system, keloid scars, neuritis, etc. Karipazim is administered by the electrophoretic method * The drug is used on an inpatient or outpatient basis.

Contraindications:

Increased individual sensitivity to the drug; Pregnancy, lactation; Caripazim should not be administered subcutaneously, intramuscularly or intravenously; Caripazim should not be used in cases of acute inflammation, as well as in the case of sequestration of the disc herniation and sequestration of the spinal canal (foramenal location).

Side effects and Special precautions:

Caripazim may cause an allergic reaction. Antihistamine therapy is given in case of hypersensitivity expressed in the form of itching activities and increased temperature.

Interaction with other medicinal products:

Interaction of clinical significance with other medicinal products has not been established.

Special instructions:

The drug does not adversely affect the ability to drive and use machines;

Release form:

Primary packaging. 350 pe lyophilized powder for solution for external use. Each vial with instructions is placed in a cardboard box..

Storage instructions:

Store at a dry place at +2 + 8°C; protect from light.

Keep out of the reach of children.

Shelf life:

2 years.

Mode of dispensing:

Dispensed without a prescription.

Manufacturer:

LEPL TSMU Iovel Kutateladze Institute of Pharmacochemistry

Address: Georgia, Tbilisi 0159, p. Sarajishvili st. №36

Phone: 253-14-94, 252-19-04

Email: ikip@tsmu.edu

Website:  www.ikip.tsmu.edu