Personnel: Principal scientific researcher M. Getia, Scientific researcher G. Moshiashvili

History: The Department of Pharmaceutical Analysis and Standardization was established at the TSMU Iovel Kutateladze Institute of Pharmacochemistry in 2017, before that it existed as a Laboratory of analysis.

Goals  & Objectives: The aims of the department are the development of new methods of analysis and standardisation of biologically active compounds, extracts, substances and dosage forms.

To achieve the aims, the Department of Pharmaceutical Analysis and Standardization performs the following tasks:

• Characterization of biologically active extracts, enriched fractions and purified substances of plant or mineral origin.
• Qualitative and quantitative analysis of abovementioned substances using physical, chemical and physical-chemical methods of analysis.
• Identification of biologically active substances from biologically active extracts and enriched fractions, development of methods for their separation and isolation.
• Updating or development of new methods of drug analysis for the drugs or biological active substances developed at the TSMU I.K. Institute of Pharmacochemistry.

Scientific Areas:

Pharmaceutical chemistry, Pharmacy

Research Methodology:

For analyses and standardization of Biological active extracts, enriched fractions and Individual compounds the following methods are used: Methods of chemical analyses; UV/VIS and IR spectrometry (Jasco V730; Jasco FT/IR 4600); Polarography (Anton Paar MCP 200); TLC; HPLC (Agilent technologies 1260 infinity, Agilent technologies 1260 infinity with fraction collector and preparative column) and GC (Agilent technologies 7890B); mass-spectrometry (Agilent technologies 6420 Triple Quad LC/MS) and potentiometry (Cyberscan).

Academic area:

The Department of Pharmaceutical Analyses and Standardization is actively involved in the training of undergraduate and postgraduate students of the Faculty of Pharmacy at Tbilisi State Medical University.

Expertise/Consulting Area:

Staff scientists of the Department of Pharmaceutical Analysis and Standardization are actively involved in the expertise of master's and doctoral theses.

Results

Analysis of extracts, enriched fractions and biologically active substances, isolated from different species of plants spread and introduced in Georgia was performed using optical (polarography, refractometry, spectrophotometry - UV, visible and infrared light), mass spectrometry and chemical methods of analysis.

New methods of qualitative and quantitative analysis of drugs developed in the Institute were developed and existing ones were enhanced.

The obtained results were made public via articles in various peer-reviewed scientific journals and reported on conferences in the form of oral and poster presentations.